Fresh analysis suggests that people who come off new weight-loss injections like Mounjaro or Wegovy can put back on shed pounds much more quickly than those who stop traditional diet and exercise plans.
Findings released in a prominent medical journal shows that while obese people often shed substantial amounts of their body weight while using the jabs, the weight returns at an average rate of 0.8 kg per month upon discontinuation.
"Users purchasing such medications should be informed of the danger of quick weight regain when the therapy ends," cautioned expert Dr. Susan Jebb.
Such speed of recovery implies a return to pre-treatment weight in about 18 months.
Comparing Therapies
The research, which reviewed 37 of studies involving over 9,000 of patients, compared the effects of these new drugs with older methods.
Researchers point out that people who shed pounds through dieting generally experience a less rapid weight regain—perhaps 100 grams monthly—after stopping.
Understanding the Rapid Regain
Doctors suggest the mode of action of the jabs explains the accelerated regain.
The injections copy a body's own chemical called GLP-1, which helps regulate appetite.
"Long-term administration of the hormone levels far above than the body's typical production could lead to the system to produce less of its endogenous hormone, and may also diminish sensitivity to its actions," explained Dr. Adam Collins, a nutrition specialist.
"Stopping of this hormone supplement results in appetite is uncontrolled, making excessive eating much more probable."
A Lifelong Issue?
Medical guidelines recommend the jabs for people with weight-linked medical conditions, accompanied by prescribed lifestyle changes.
Professionals argue that, due to the high risk of relapse, the treatment is often life-long.
This perspective is echoed by drug manufacturers, who note that the results "underscore the chronic nature of obesity," comparing it to managing conditions like high blood pressure.
User Testimonies
People who have stopped the medication explain a sudden resurgence of hunger.
"I experienced a trigger flipping and you're instantly ravenous," said a patient.
The struggle is exacerbated if users have not adopted sustainable lifestyle or habit modifications during treatment.
Widespread Interest
Recent estimates suggest that a significant number of people in the UK have used these injections in the past year, with demand remaining high.
- Use is greater among females compared to men.
- The middle-aged age group shows the highest usage rates.
- A large proportion obtain the medications through private prescriptions rather than the NHS.
In conclusion, researchers stress that while the jabs are powerful agents for shedding pounds, they are not a magic cure and long-term success likely depends on combined behavioural management.
